COMPLETEDN/A

Hormone Replacement Therapy and Prothrombotic Variants

To examine in postmenopausal women the potential interactions of hormone replacement therapy with other blood clotting factors on the risk of cardiovascular diseases such as heart attack or stroke.

Sponsor

University of Washington

Enrollment

1,000 participants

Sites

0 locations

Start Date

September 2002

Completion

August 2008

Cardiovascular DiseasesHeart DiseasesCerebrovascular AccidentMyocardial InfarctionHypertension

Enrollment & Timeline

Completed

Target N

1,000

participants

Sites

locations

Duration

5.9 years

total trial span

Rate

pts/month needed

View on ClinicalTrials.gov

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Primary Outcomes

Myocardial Infarction or Stroke

Retrospective

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Eligibility

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Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis.

Psaty Bruce M, Lumley Thomas, Furberg Curt D et al.JAMA2003

DOI PubMed

Medications and cardiovascular health in older adults: room for improvement in prevention and treatment.

Rhoads Caroline S, Psaty Bruce M, Olson Jean L et al.The American journal of geriatric cardiology2004

DOI PubMed

Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis.

Smith Nicholas L, Heckbert Susan R, Lemaitre Rozenn N et al.JAMA2004

DOI PubMed

Association of cholesterol with stroke risk varies in stroke subtypes and patient subgroups.

Tirschwell D L, Smith N L, Heckbert S R et al.Neurology2005

DOI PubMed

Recurrence of Non-Small Cell Lung Cancer With Visceral Pleural Invasion: A Secondary Analysis of a Randomized Clinical Trial.

Altorki Nasser, Wang Xiaofei, Damman Bryce et al.JAMA oncology2024

DOI PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

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Fetching protocol from ClinicalTrials.gov…

COMPLETEDN/A

Hormone Replacement Therapy and Prothrombotic Variants

To examine in postmenopausal women the potential interactions of hormone replacement therapy with other blood clotting factors on the risk of cardiovascular diseases such as heart attack or stroke.

Sponsor

University of Washington

Enrollment

1,000 participants

Sites

0 locations

Start Date

September 2002

Completion

August 2008

Cardiovascular DiseasesHeart DiseasesCerebrovascular AccidentMyocardial InfarctionHypertension